SKU: AN200072P-100ul-ELS
MAPKAPK3/MK3 Monoclonal Antibody
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | IHC-P |
| Label | Unconjugated |
| Synonyms | MDPT, MAPKAP, MAPKAP-K, MAPKAPK3, 3PK, MAPKAP-K3, MAPKAP3, MAPKAPK-3, MDPT3, MK-3, anti MAPKAPK3, Chromosome 3p kinase, EC 2.7.11.1, MAP kinase-activated protein kinase 3, MAPK activated protein kinase 3, MAPK3, MAPK-activated protein kinase 3, MAPKAP kinase 3, MAPKAPK 3, MDPT326, Mitogen activated protein kinase activated protein kinase, Mitogen activated protein kinase activated protein kinase 3, mitogen-activated protein kinase-activated protein kinase 3 |
| UniProt ID | Q16644 |
| Immunogen | Recombinant Human MAPKAPK3/MK3 Protein |
| Background | This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E44, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. Alternate splicing results in multiple transcript variants that encode the same protein. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG2a |
| Concentration | 1 mg/mL |
| Clone Name | 4B6 |
| Buffer | 0.2 μm filtered solution in PBS |
| Clonality | Monoclonal |
| Host | Mouse |
Resources
PDF
Datasheet
Catalog Number
AN200072P-100ul-ELS
Name
MAPKAPK3/MK3 Monoclonal Antibody
Price(100 ul)
Pack Size
100 ul