SKU: TA343697-OR
MAFF Rabbit Polyclonal Antibody
In Stock
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | WB |
| Label | Unconjugated |
| Synonyms | hMafF; OTTHUMP00000028701; transcription factor MAFF; U-MAF; v-maf avian musculoaponeurotic fibrosarcoma oncogene family protein F; v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) |
| Gene ID | 23764 |
| Accession No. | NM_152878 |
| UniProt ID | Q9ULX9 |
| Background | MAFF is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. MAFF can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. MAFF may also be involved in the cellular stress response.The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Two transcript variants encoding the same protein have been found for this gene. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Clonality | Polyclonal |
| Host | Rabbit |
Resources
PDF
Datasheet
Catalog Number
TA343697-OR
Name
MAFF Rabbit Polyclonal Antibody
Price(10 mg)
Pack Size
10 mg