SKU: E-AB-60650-200ul-ELS
(KO Validated) EIF4E Polyclonal Antibody
In Stock
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Application | IHC, IF |
| Label | Unconjugated |
| Synonyms | AUTS19, CBP, EIF4E1, EIF4EL1, EIF4F, eIF-4E, EIF4E |
| Gene ID | 1977 |
| UniProt ID | P06730 |
| Immunogen | A synthetic peptide of human EIF4E (NP_001959.1). |
| Background | The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Concentration | 1mg/mL |
| Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Clonality | Polyclonal |
| Host | Rabbit |
Resources
PDF
Datasheet
Catalog Number
E-AB-60650-200ul-ELS
Name
(KO Validated) EIF4E Polyclonal Antibody
Price(20000 ul)
Pack Size