SKU: A77593-100-EP
KDM2A Polyclonal Antibody
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse |
| Application | WB, ELISA |
| Label | Unconjugated |
| Synonyms | FBL7; CXXC8; FBL11; FBXL11; JHDM1A; LILINA; KDM2A |
| Accession No. | NP036440 |
| UniProt ID | Q9Y2K7 |
| Immunogen | Synthetic peptide. Please contact BioCat for more information. |
| Background | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Concentration | 1.62 mg/mL |
| Buffer | Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3. |
| Clonality | Polyclonal |
| Host | Rabbit |
Resources
PDF
Datasheet
Catalog Number
A77593-100-EP
Name
KDM2A Polyclonal Antibody
Price(100 ul)
Pack Size
100 ul