SKU: E-AB-52020-120ul-ELS
IL4R Polyclonal Antibody
In Stock
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | IHC |
| Label | Unconjugated |
| Synonyms | CD124, IL 4R alpha, IL-4 receptor subunit alpha, IL-4-binding protein, IL-4R subunit alpha, IL-4R-alpha, IL-4RA, IL4-BP, Il4r, IL4R nirs variant 1, IL4RA, IL4RA, Interleukin 4 receptor alpha chain, Interleukin 4 receptor, sIL4Ralpha/prot, Soluble IL-4 receptor subunit alpha, Soluble IL-4R-alpha, Soluble interleukin-4 receptor subunit alpha |
| Accession No. | NP000409 |
| UniProt ID | P24394 |
| Immunogen | Synthetic peptide of human IL4R |
| Background | This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Concentration | 1.26 mg/mL |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Clonality | Polyclonal |
| Host | Rabbit |
Resources
PDF
Datasheet
Catalog Number
E-AB-52020-120ul-ELS
Name
IL4R Polyclonal Antibody
Price(12000 ul)
Pack Size