SKU: A76232-100-EP
IL4R Polyclonal Antibody
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Application | WB, IHC-P, ELISA |
| Label | Unconjugated |
| Synonyms | CD124; IL4RA; IL-4RA; IL4R |
| Accession No. | NP000409 |
| UniProt ID | P24394 |
| Immunogen | Recombinant protein (or fragment). Please contact BioCat for more information. |
| Background | This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Concentration | 1.26 mg/mL |
| Buffer | Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3. |
| Clonality | Polyclonal |
| Host | Rabbit |
Resources
PDF
Datasheet
Catalog Number
A76232-100-EP
Name
IL4R Polyclonal Antibody
Price(100 ul)
Pack Size
100 ul