SKU: EA102650-OR
Human Heparin Cofactor II (SERPIND1) ELISA KIT
Blue Ice
Colorimetric
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Sensitivity | <0.1ng/ml |
| Detection Range | 0.78ng/ml-50ng/ml |
| Design Principle | Sandwich |
| Detection Method | Colorimetric |
| Target Name | SERPIND1 |
| Gene ID | 3053 |
| Specificity | This kit is used for quantitative detection of Human Serpin D1 |
| Target Background | Heparin cofactor II (HCII), a protein encoded by the SERPIND1 gene, is a coagulation factor that inhibits IIa, and is a cofactor for heparin and dermatan sulfate. It is mapped to 22q11.21. This gene belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. This gene encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency. |
| Accession No. | NM_000185 |
| Assay Time | 3.5 hours incubations; 1 hour washing and analyzing samples |
Resources
PDF
Manual
Catalog Number
EA102650-OR
Name
Human Heparin Cofactor II (SERPIND1) ELISA KIT
Price(8 x 12 Well Strip Plate)
Pack Size
8 x 12 Well Strip Plate