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SKU: A59396-100-EP

HMGN3 Polyclonal Antibody, FITC Conjugated

Blue Ice

Specifications

Specification Details
Species Reactivity Human
Application ELISA
Label FITC
Synonyms High mobility group nucleosome-binding domain-containing protein 3, HMGN3, TRIP7, PNAS-24, Thyroid receptor-interacting protein 7, TR-interacting protein 7, TRIP-7
UniProt ID Q15651
Immunogen Recombinant Human High mobility group nucleosome-binding domain-containing protein 3 protein (1-77AA)
Background Binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. Affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion. Regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors. Regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. May play a role in ocular development and astrocyte function.
Primary / Secondary Primary Antibody
Isotype IgG
Buffer 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4
Clonality Polyclonal
Host Rabbit
Catalog Number
A59396-100-EP
Name
HMGN3 Polyclonal Antibody, FITC Conjugated
Price(100 ul)
Pack Size
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