SKU: A76083-100-EP
HLA-DPB1 Polyclonal Antibody
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Application | WB, IHC-P, ELISA |
| Label | Unconjugated |
| Synonyms | DPB1; HLA-DP; HLA-DPB; HLA-DP1B; HLA-DPB1 |
| Accession No. | P04440 |
| UniProt ID | P04440 |
| Immunogen | Recombinant protein (or fragment). Please contact BioCat for more information. |
| Background | HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Concentration | Lot specific. Please inquire or refer to the datasheet included in the product pouch. |
| Buffer | Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3. |
| Additional Information | Conjugation service and the corresponding secondary antibody are available. |
| Clonality | Polyclonal |
| Host | Rabbit |
Catalog Number
A76083-100-EP
Name
HLA-DPB1 Polyclonal Antibody
Price(100 ul)
Pack Size
100 ul