SKU: TA324175-OR
Fbx32 (FBXO32) Rabbit Polyclonal Antibody
In Stock
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Application | IHC, WB |
| Label | Unconjugated |
| Synonyms | Fbx32; MAFbx |
| Gene ID | 114907 |
| Accession No. | NM_001242463 |
| UniProt ID | Q969P5 |
| Background | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Clonality | Polyclonal |
| Host | Rabbit |
Resources
PDF
Datasheet
Catalog Number
TA324175-OR
Name
Fbx32 (FBXO32) Rabbit Polyclonal Antibody
Price(10 ml)
Pack Size
10 ml