SKU: E-AB-F1227T-50Tests-ELS
Elab Fluor®Violet 610 Anti-Rat CD45 Antibody[OX-1]
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Rat |
| Application | FCM |
| Label | Elab Fluor®Violet 610 |
| Synonyms | LCA, Ly-5, T200, Leukocyte common antigen, Ptprc, Receptor-type tyrosine-protein phosphatase C |
| Gene ID | 19265 |
| UniProt ID | P04157 |
| Background | CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro. |
| Primary / Secondary | Primary Antibody |
| Isotype | Mouse IgG1, κ |
| Clone Name | OX-1 |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Clonality | Monoclonal |
| Host | Mouse |
Resources
PDF
Datasheet
Catalog Number
E-AB-F1227T-50Tests-ELS
Name
Elab Fluor®Violet 610 Anti-Rat CD45 Antibody[OX-1]
Price(50 tests)
Pack Size