SKU: E-AB-F1037M1-100Tests-ELS
Elab Fluor®700 Anti-Human CD40 Antibody[3A8]
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | FCM |
| Label | Elab Fluor®700 |
| Synonyms | B-cell surface antigen CD40, Bp50, CD40, CD40L receptor, Cd40, Tnfrsf5, Tumor necrosis factor receptor superfamily member 5 |
| Gene ID | 958 |
| UniProt ID | P25942 |
| Background | CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis. |
| Primary / Secondary | Primary Antibody |
| Isotype | Mouse IgG2a, κ |
| Clone Name | 3A8 |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Clonality | Monoclonal |
| Host | Mouse |
Resources
PDF
Datasheet
Catalog Number
E-AB-F1037M1-100Tests-ELS
Name
Elab Fluor®700 Anti-Human CD40 Antibody[3A8]
Price(100 tests)
Pack Size