SKU: E-AB-F0994UM-25ug-ELS
Elab Fluor® 647 Anti-Mouse CD86 Antibody[GL-1]
In Stock
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Mouse |
| Application | FCM |
| Label | Elab Fluor®647 |
| Synonyms | Activation B7-2 antigen, Cd86, ETC-1, Early T-cell costimulatory molecule 1, T-lymphocyte activation antigen CD86 |
| Gene ID | 12524 |
| UniProt ID | P42082 |
| Background | CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells. |
| Primary / Secondary | Primary Antibody |
| Isotype | Rat IgG2a, κ |
| Concentration | 0.5 mg/mL |
| Clone Name | GL-1 |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Clonality | Monoclonal |
| Host | Rat |
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Datasheet
Catalog Number
E-AB-F0994UM-25ug-ELS
Name
Elab Fluor� 647 Anti-Mouse CD86 Antibody[GL-1]
Price(2500 ug)
Pack Size