SKU: A81953-100-EP
EIF4G1 Polyclonal Antibody
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | WB, IHC-P, IP, ELISA |
| Label | Unconjugated |
| Synonyms | P220; EIF4F; EIF4G; EIF4GI; PARK18; EIF-4G1; EIF4G1 |
| UniProt ID | Q04637 |
| Immunogen | Synthetic peptide. Please contact BioCat for more information. |
| Background | The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Buffer | Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3. |
| Clonality | Polyclonal |
| Host | Rabbit |
Catalog Number
A81953-100-EP
Name
EIF4G1 Polyclonal Antibody
Price(100 ul)
Pack Size
100 ul