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SKU: A67130-020-EP

EIF3C Polyclonal Antibody

Blue Ice

Specifications

Specification Details
Species Reactivity Human
Application ELISA, WB, IHC, IF
Label Unconjugated
Synonyms Eukaryotic translation initiation factor 3 subunit C, Eukaryotic translation initiation factor 3 subunit 8, EIF3C
UniProt ID Q99613
Immunogen Recombinant Human Eukaryotic translation initiation factor 3 subunit C protein (201-500AA)
Background Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Primary / Secondary Primary Antibody
Isotype IgG
Buffer 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4
Clonality Polyclonal
Host Rabbit
Catalog Number
A67130-020-EP
Name
EIF3C Polyclonal Antibody
Price(20 ul)
Pack Size
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