SKU: A67130-050-EP
EIF3C Polyclonal Antibody
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | ELISA, WB, IHC, IF |
| Label | Unconjugated |
| Synonyms | Eukaryotic translation initiation factor 3 subunit C, Eukaryotic translation initiation factor 3 subunit 8, EIF3C |
| UniProt ID | Q99613 |
| Immunogen | Recombinant Human Eukaryotic translation initiation factor 3 subunit C protein (201-500AA) |
| Background | Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Buffer | 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4 |
| Clonality | Polyclonal |
| Host | Rabbit |
Catalog Number
A67130-050-EP
Name
EIF3C Polyclonal Antibody
Price(50 ul)
Pack Size