SKU: E-AB-17896-200ul-ELS
DUSP27 Polyclonal Antibody
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse |
| Application | IHC |
| Label | Unconjugated |
| Synonyms | C130085G02Rik, DUS27, DUSP27, Gm209, Inactive dual specificity phosphatase 27, RGD1560598 |
| Accession No. | NP001073895 |
| UniProt ID | Q5VZP5 |
| Immunogen | Synthetic peptide of human DUSP27 |
| Background | Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members, including MAPK/ERK, SAPK/JNK and p38. DUSP27 (dual specificity phosphatase 27), also known as FMDSP or DUPD1 (dual specificity phosphatase and pro isomerase domain containing 1), is a 220 amino acid cytoplasmic protein that belongs to the protein-tyrosine phosphatase family. Expressed in skeletal muscle, liver and adipose tissue, DUSP27 may play a role in energy metabolism. The gene encoding DUSP27 is referred to as DUPD1 and maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Concentration | 1.92 mg/mL |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Clonality | Polyclonal |
| Host | Rabbit |
Resources
PDF
Datasheet
Catalog Number
E-AB-17896-200ul-ELS
Name
DUSP27 Polyclonal Antibody
Price(200 ul)
Pack Size