SKU: E-AB-14961-200ul-ELS
DRG1 Polyclonal Antibody
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse |
| Application | WB |
| Label | Unconjugated |
| Synonyms | Developmentally regulated GTP binding protein 1, Developmentally-regulated GTP-binding protein 1, DKFZp434N1827, DRG 1, DRG-1, DRG1, DRG1, NEDD 3, NEDD-3, NEDD3, Neural precursor cell expressed developmentally down regulated protein 3, Neural precursor cell expressed developmentally down-regulated protein 3 |
| Accession No. | BC019285 |
| UniProt ID | Q9Y295 |
| Immunogen | Recombinant protein of human DRG1 |
| Background | DRG1 (developmentally regulated GTP binding protein 1), also known as NEDD3 (neural precursor cell expressed developmentally down-regulated protein 3), is a 367 amino acid protein that localizes to the cytoplasm and belongs to the GTP1/OBG family. Expressed at high levels in heart, kidney and skeletal muscle and at lower levels in brain, liver, placenta, lung, colon and spleen, DRG1 binds to TAL1 and TAL2 and is thought to play a role in cell proliferation and differentiation, as well as in apoptosis, suggesting a role in tumor formation and metastasis. DRG1 is subject to polyubiquitination and sumoylation, the former of which induces proteolytic degradation. The gene encoding DRG1 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Concentration | 0.6 mg/mL |
| Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Clonality | Polyclonal |
| Host | Rabbit |
Resources
PDF
Datasheet
Catalog Number
E-AB-14961-200ul-ELS
Name
DRG1 Polyclonal Antibody
Price(200 ul)
Pack Size