SKU: A50188-100-EP
DAPK2 Polyclonal Antibody, Biotin Conjugated
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | ELISA |
| Label | Biotin |
| Synonyms | DAP kinase 2, DAP-kinase-related protein 1, DRP-1, DAPK2 |
| UniProt ID | Q9UIK4 |
| Immunogen | Recombinant Human Death-associated protein kinase 2 protein (222-370AA) |
| Background | Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation. Isoform 2 is not regulated by calmodulin. It can phosphorylate MYL9. It can induce membrane blebbing and autophagic cell death. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Buffer | 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4 |
| Clonality | Polyclonal |
| Host | Rabbit |
Catalog Number
A50188-100-EP
Name
DAPK2 Polyclonal Antibody, Biotin Conjugated
Price(100 ul)
Pack Size