SKU: A58700-100-EP
CXADR Polyclonal Antibody, FITC Conjugated
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | ELISA |
| Label | FITC |
| Synonyms | Coxsackievirus and adenovirus receptor, CAR, hCAR, CXADR, CAR, CVB3-binding protein, Coxsackievirus B-adenovirus receptor, HCVADR |
| UniProt ID | P78310 |
| Immunogen | Recombinant Human Coxsackievirus and adenovirus receptor protein (259-365AA) |
| Background | Component of the epithelial apical junction complex that may function as an homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with AMICA1/JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, AMICA1 induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Buffer | 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4 |
| Clonality | Polyclonal |
| Host | Rabbit |
Catalog Number
A58700-100-EP
Name
CXADR Polyclonal Antibody, FITC Conjugated
Price(100 ul)
Pack Size