SKU: E-AB-13179-200ul-ELS
CSTB Polyclonal Antibody
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | IHC |
| Label | Unconjugated |
| Synonyms | CHROW21, CPI B, CPI-B, CST 6, CST6, CSTB, Cystatin B (stefin B), Cystatin B, Cystatin-B, CYTB, CYTB, EPM1, EPM1A, Liver thiol proteinase inhibitor, PME, Stefin-B, STF B, STFB, ULD |
| Accession No. | NP_000091 |
| UniProt ID | P04080 |
| Immunogen | Synthetic peptide of human CSTB |
| Background | The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Concentration | 0.9 mg/mL |
| Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Clonality | Polyclonal |
| Host | Rabbit |
Resources
PDF
Datasheet
Catalog Number
E-AB-13179-200ul-ELS
Name
CSTB Polyclonal Antibody
Price(200 ul)
Pack Size