SKU: E-AB-52144-200ul-ELS
COX7A2L Polyclonal Antibody
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse |
| Application | IHC |
| Label | Unconjugated |
| Synonyms | COX7a related protein, COX7a-related protein, COX7A2L, COX7AR, COX7R, COX7RP, Cytochrome c oxidase subunit 7A-related protein, cytochrome c oxidase subunit 7A-related protein, mitochondrial, Cytochrome c oxidase subunit 7A2 like, cytochrome c oxidase subunit VII-related protein, cytochrome c oxidase subunit VIIa polypeptide 2 like, Cytochrome c oxidase subunit VIIa related protein, mitochondrial, Cytochrome c oxidase subunit VIIa-related protein, EB1, Estrogen receptor binding CpG island, mitochondrial, SIG81 |
| Accession No. | BC007095 |
| UniProt ID | O14548 |
| Immunogen | Full length fusion protein |
| Background | Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Concentration | 2.5 mg/mL |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Clonality | Polyclonal |
| Host | Rabbit |
Resources
PDF
Datasheet
Catalog Number
E-AB-52144-200ul-ELS
Name
COX7A2L Polyclonal Antibody
Price(200 ul)
Pack Size