SKU: E-AB-30003-60ul-ELS
Cleaved-CASP3 p12 (D175) Polyclonal Antibody
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | WB, IHC-p, IF |
| Label | Unconjugated |
| Synonyms | A830040C14Rik, Apopain, CASP-3, CASP3, CASP3, Casp3a, Caspase 3, Caspase 3, apoptosis-related cysteine peptidase, Caspase 3, apoptosis-related cysteine protease, Caspase 3, apoptosis-related cysteine protease a, Caspase-3 subunit p12, CC3, CPP-32, CPP32, CPP32B, Cysteine protease CPP32, EC 3.4.22.56, LICE, mldy, OTTHUMP00000165052, OTTHUMP00000165053, OTTHUMP00000165054, PARP cleavage protease, Procaspase3, Protein Yama, SCA 1, SCA-1, SREBP cleavage activity 1, Yama |
| UniProt ID | P42574 |
| Immunogen | Synthesized peptide derived from the Internal region of human Caspase-3 p12 |
| Background | Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Concentration | 1mg/mL |
| Buffer | PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4 |
| Clonality | Polyclonal |
| Host | Rabbit |
Resources
PDF
Datasheet
Catalog Number
E-AB-30003-60ul-ELS
Name
Cleaved-CASP3 p12 (D175) Polyclonal Antibody
Price(60 ul)
Pack Size