SKU: A82695-100-EP
CHM Monoclonal Antibody [2F7W2]
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | WB, ELISA |
| Label | Unconjugated |
| Synonyms | TCD; GGTA; REP-1; DXS540; HSD-32; CHM |
| UniProt ID | P24386 |
| Immunogen | Synthetic peptide. Please contact BioCat for more information. |
| Background | This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia; also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternatively spliced transcript variants have been found for this gene. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Clone Name | 2F7W2 |
| Buffer | Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3. |
| Clonality | Monoclonal |
| Host | Rabbit |
Catalog Number
A82695-100-EP
Name
CHM Monoclonal Antibody [2F7W2]
Price(100 ul)
Pack Size
100 ul