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SKU: E-AB-16322-60ul-ELS

CD54 Polyclonal Antibody

Blue Ice

Specifications

Specification Details
Species Reactivity Human
Application WB, IHC
Label Unconjugated
Synonyms Antigen identified by monoclonal BB2, BB 2, BB2, CD 54, CD_antigen=CD54, CD54, Cell surface glycoprotein P3.58, Human rhinovirus receptor, ICAM 1, ICAM-1, ICAM1, ICAM1, intercellular adhesion molecule 1 (CD54), human rhinovirus receptor, Intercellular adhesion molecule 1, Major group rhinovirus receptor, MALA 2, MALA2, MyD 10, MyD10, P3.58, Surface antigen of activated B cells, BB2
Accession No. NP_000192
UniProt ID P05362
Immunogen Synthetic peptide of human ICAM1
Background This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
Primary / Secondary Primary Antibody
Isotype IgG
Concentration 0.4 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Clonality Polyclonal
Host Rabbit

Resources

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Datasheet

Catalog Number
E-AB-16322-60ul-ELS
Name
CD54 Polyclonal Antibody
Price(60 ul)
Pack Size
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