SKU: E-AB-11038-60ul-ELS
CCDC106 Polyclonal Antibody
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse |
| Application | IHC |
| Label | Unconjugated |
| Synonyms | CC106, Ccdc106, Coiled-coil domain-containing protein 106, HSU79303, Protein predicted by clone 23882, ZNF581 |
| Accession No. | BC000412 |
| UniProt ID | Q9BWC9 |
| Immunogen | Recombinant protein of human CCDC106 |
| Background | The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Concentration | 0.3 mg/mL |
| Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Clonality | Polyclonal |
| Host | Rabbit |
Resources
PDF
Datasheet
Catalog Number
E-AB-11038-60ul-ELS
Name
CCDC106 Polyclonal Antibody
Price(60 ul)
Pack Size