SKU: TA504636S-OR
CAMLG Mouse Monoclonal Antibody [Clone ID: OTI1H3]
In Stock
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Application | FC, IF, WB |
| Label | Unconjugated |
| Synonyms | CAML |
| Gene ID | 819 |
| Accession No. | NM_001745 |
| UniProt ID | P49069 |
| Background | The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq]. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG2b |
| Clone Name | OTI1H3 |
| Clonality | Monoclonal |
| Host | Mouse |
Resources
PDF
Datasheet
Catalog Number
TA504636S-OR
Name
CAMLG Mouse Monoclonal Antibody [Clone ID: OTI1H3]
Price(3000 ul)
Pack Size