SKU: E-AB-F1090B-100ug-ELS
Biotin Anti-Mouse CD103 Antibody[M290]
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Mouse |
| Application | FCM |
| Label | Biotin |
| Synonyms | CD103, Integrin alpha M290, Integrin alpha-E, Itgae |
| Gene ID | 16407 |
| UniProt ID | Q60677 |
| Background | CD103 is a type I transmembrane glycoprotein known as αE integrin or Integrin αIEL chain. It belongs to the integrin family and is primarily found on intestinal intraepithelial lymphocytes (IEL). CD103 is also expressed on a subpopulation of lamina propria T cells, epithelial dendritic cells, lamina propria-derived dendritic cells, and a small subset of peripheral lymphocytes. T regulatory cells express high level of CD103. The CD103 expression on lymphocytes can be induced upon activation and TGF-β stimulation. In association with integrin β7, CD103 is expressed as αE/β7 heterodimer. Mature CD103 protein can be cleaved into 2 chains, a 150 kD (C-terminal) chain and a 25 kD (N-terminal) chain, which remain linked by disulfide bonds. CD103 binds to E-cadherin and mediates homing of lymphocytes to the intestinal epithelium. |
| Primary / Secondary | Primary Antibody |
| Isotype | Rat IgG2a, κ |
| Concentration | 0.5 mg/mL |
| Clone Name | M290 |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Clonality | Monoclonal |
| Host | Rat |
Resources
PDF
Datasheet
Catalog Number
E-AB-F1090B-100ug-ELS
Name
Biotin Anti-Mouse CD103 Antibody[M290]
Price(100 ug)
Pack Size