SKU: T6630-GVO-ABM
B4GalT2-/-B4GalT3-/-B4GalT4-/-ST3Gal3-/-ST3Gal6-/- CRISPR Knockout CHO-K1 Cell Line
Chinese Hamster (C. griseus)
Dry Ice
Specifications
| Specification | Details |
|---|---|
| Organism | Chinese Hamster (C. griseus) |
| Tissue Origin | Ovary |
| Additional Information | B4GalT2⁻/⁻ B4GalT3⁻/⁻ B4GalT4⁻/⁻ ST3Gal3⁻/⁻ ST3Gal6⁻/⁻ CRISPR Knockout CHO-K1 Cell Line is a genetically engineered Chinese hamster ovary (CHO-K1) model in which B4GalT1, B4GalT2, B4GalT3, ST3Gal3, and ST3Gal6 genes have been completely deleted, leaving only B4GalT4 expressed. This quintuple knockout provides a stable and heritable system for studying glycosylation pathways, carbohydrate biosynthesis, and protein glycoengineering, particularly for investigating β-1,4-galactosylation without competing α-2,3 sialylation. The cell line serves as a robust platform for functional genomics, mechanistic research, and optimization of therapeutic protein production |
Catalog Number
T6630-GVO-ABM
Name
B4GalT2-/-B4GalT3-/-B4GalT4-/-ST3Gal3-/-ST3Gal6-/- CRISPR Knockout CHO-K1 Cell Line
Price(1 x 10^6 cells)
Pack Size
1 x 10^6 cells