axoCells Human iPSC-Derived Cortical Neuron Cells, Media, Supplements and Coating Kit, Alzheimer's Disease (PSEN1 L286V) 38 yo female donor, >1.5 million cells
Specifications | |
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Product Category: | Kits incl. iPSC-Derived Cells, Media & More |
Research Area: | Neuroscience |
Product Description
axoCells™ Human iPSC-Derived Cortical Neuron Cells, Media, Supplements and Coating Kit is optimized for maturation of cortical neurons for neuroscience research. NSCs made from iPSCs generated from an 38-year-old Alzheimer's Disease (APOE4 HOM) female donor's dermal fibroblasts.
- Derived from human iPSCs
- Convenient kit format containing cells, media, supplements and coating
- Assay-ready in 20 days
- Express over 12 of the key markers (including FOXG1, PAX6 and vimentin)
- Demonstrated functionality in advanced in vitro models including co-culture and tri-culture
Kit Content
- Human iPSC-Derived Neural Stem Cells – Alzheimer’s Disease Patient (≥1.5 million cells)
- Neural Maintenance Medium (500 ml)
- NeurOne Cortical Neuron Kit
- Neural Plating Medium (30 ml)
- BDNF (10 µg)
- SureBond-XF Xeno-free Coating Reagent (1ml)
Limited License Terms
Axol Bioscience's Limited License TermsGenetically Modified Organism (GVO)
See General Terms.
Product Citations
- Xiong J, Kang SS, Wang M, Wang Z, Xia Y, Liao J, Liu X, Yu SP, Zhang Z, Ryu V, Yuen T, Zaidi M, Ye K. (2023) FSH and ApoE4 contribute to Alzheimer's disease-like pathogenesis via C/EBPβ/δ-secretase in female mice Nature Communications
- Chen G, Kang SS, Wang Z, Ahn EH, Xia Y, Liu X, Sandoval IM, Manfredsson FP, Zhang Z, Ye K. (2021) Netrin-1 receptor UNC5C cleavage by active δ-secretase enhances neurodegeneration, promoting Alzheimer's disease pathologies.
- Xia Y, Wang ZH, Zhang J, Liu X, Yu SP, Ye KX, Wang JZ, Ye K, Wang XC. (2020) C/EBPβ is a key transcription factor for APOE and preferentially mediates ApoE4 expression in Alzheimer's disease Molecular Psychiatry
- Zollo A, Allen Z, Rasmussen HF, Iannuzzi F, Shi Y, Larsen A, Maier TJ, Matrone C. (2017) Sortilin-Related Receptor Expression in Human Neural Stem Cells Derived from Alzheimer's Disease Patients Carrying the APOE Epsilon 4 Allele Neural Plasticity
- Catalog Number
ax5112-GVO-AX - Supplier
Axol Bioscience - Size
- Shipping
Dry Ice & Blue Ice
Price
3.078,00 €