axoCells Human iPSC-Derived Astrocytes, Male

Product Description

axoCells Human iPSC-Derived Astrocytes (≥1 million cells) for neuroscience research. Astrocytes made from iPSCs which were generated from a 40-50 year old male donor's fibroblasts.

• Assay ready in just 2 days
• Express the key markers (incl. GFAP and S100B) with low expression of Nestin (an NSC marker)
• Demonstrated functionality in advanced in vitro models
• Specifically developed for use in powerful in vitro monoculture models and complex co-culture systems for research and drug discovery

With Axol, you can rely on robust, physiologically relevant astrocytes that express the seven key markers of primary human astrocytes, with low expression of Nestin (a marker of neural stem cells). That means robust, physiologically relevant models of Alzheimer’s Disease, Parkinson’s Disease and ALS. 

Astrocytes are star-shaped glial cells that play crucial roles in the central nervous system (CNS), including neuronal support, regulation of neurotransmitter levels, maintenance of the blood-brain barrier, and modulation of synaptic activity. Dysfunction of astrocytes has been implicated in various neurological disorders including Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis.

Human iPSC-derived astrocytes can be used to study neurodegenerative disease processes in vitro. Astrocytes are particularly useful when placed in co-culture with other neurons and neuroinflammatory cells to better mimic the complex interplay of cell types in the human brain.

Supporting Data

Figure 1: Marker Expression. The expression of these markers highlights that Axol’s Human iPSC astrocytes are physiologically representative of human primary astrocytes.