SKU: E-AB-18330-20ul-ELS
ATF6B Polyclonal Antibody
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse |
| Application | WB, IHC |
| Label | Unconjugated |
| Synonyms | ATF6B, CREBL1, G13, Cyclic AMP-dependent transcription factor ATF-6 beta, cAMP-dependent transcription factor ATF-6 beta, Activating transcription factor 6 beta, ATF6-beta, Protein G13, cAMP response element-binding protein-related protein, |
| Accession No. | BC008394 |
| UniProt ID | Q99941 |
| Immunogen | Fusion protein of human ATF6B |
| Background | The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum, however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Concentration | 0.5 mg/mL |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Clonality | Polyclonal |
| Host | Rabbit |
Resources
PDF
Datasheet
Catalog Number
E-AB-18330-20ul-ELS
Name
ATF6B Polyclonal Antibody
Price(20 ul)
Pack Size