SKU: E-AB-60228-120ul-ELS
ASC / TMS1 Polyclonal Antibody
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Application | WB, IF |
| Label | Unconjugated |
| Synonyms | PYCARD, ASC, CARD5, TMS, TMS-1, TMS1, PYD and CARD domain containing, ASC / TMS1 |
| Gene ID | 29108 |
| UniProt ID | Q9ULZ3 |
| Immunogen | Recombinant fusion protein of human ASC / TMS1 (NP_037390.2). |
| Background | This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm, however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Concentration | 1mg/mL |
| Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Clonality | Polyclonal |
| Host | Rabbit |
Resources
PDF
Datasheet
Catalog Number
E-AB-60228-120ul-ELS
Name
ASC / TMS1 Polyclonal Antibody
Price(120 ul)
Pack Size