SKU: TA322340-OR
APIP Rabbit Polyclonal Antibody
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse |
| Application | IHC, WB |
| Label | Unconjugated |
| Synonyms | APIP2; CGI-29; CGI29; hAPIP; MMRP19 |
| Gene ID | 51074 |
| Accession No. | NM_015957 |
| UniProt ID | Q96GX9 |
| Background | APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regulator of ischemic/hypoxic injury.The protein highly expressed in skeletal muscle and heart and binds to the CARD of Apaf-1 in competition with caspase-9. Exogenous APIP inhibits cytochrome c-induced activation of caspase-3 and caspase-9, and suppresses cell death triggered by mitochondrial apoptotic stimuli through inhibiting the downstream activity of cytochrome c released from mitochondria. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Clonality | Polyclonal |
| Host | Rabbit |
Resources
PDF
Datasheet
Catalog Number
TA322340-OR
Name
APIP Rabbit Polyclonal Antibody
Price(0.1 ml)
Pack Size
0.1 ml