SKU: A77384-100-EP
APC Monoclonal Antibody [8X7Q1]
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Application | WB, IP, ELISA |
| Label | Unconjugated |
| Synonyms | GS; DP2; DP3; BTPS2; DESMD; DP2.5; PPP1R46; APC |
| UniProt ID | P25054 |
| Immunogen | Synthetic peptide. Please contact BioCat for more information. |
| Background | This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Mutations in the APC gene have been found to occur in most colorectal cancers, where disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Clone Name | 8X7Q1 |
| Buffer | Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3. |
| Clonality | Monoclonal |
| Host | Rabbit |
Catalog Number
A77384-100-EP
Name
APC Monoclonal Antibody [8X7Q1]
Price(100 ul)
Pack Size
100 ul