SKU: E-AB-F1028E-100Tests-ELS
APC Anti-Mouse CD40 Antibody[FGK4.5/FGK45]
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Mouse |
| Application | FCM |
| Label | APC |
| Synonyms | B-cell surface antigen CD40, Bp50, CD40, CD40L receptor, Cd40, Tnfrsf5, Tumor necrosis factor receptor superfamily member 5 |
| Gene ID | 21939 |
| UniProt ID | P27512 |
| Background | CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation. |
| Primary / Secondary | Primary Antibody |
| Isotype | Rat IgG2a, κ |
| Concentration | 5 μL/Test |
| Clone Name | FGK4.5/FGK45 |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Clonality | Monoclonal |
| Host | Rat |
Resources
PDF
Datasheet
Catalog Number
E-AB-F1028E-100Tests-ELS
Name
APC Anti-Mouse CD40 Antibody[FGK4.5/FGK45]
Price(100 tests)
Pack Size