SKU: 102-26988-RB
Anti-WISP3 (Center) Antibody
In Stock
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | WB, IHC-P |
| Label | Unconjugated |
| Gene ID | 8838 |
| Accession No. | O95389 |
| Immunogen | This WISP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-335 amino acids from the Central region of human WISP3. |
| Background | WISP3 is a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. WISP3 is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of the WISP3 gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. |
| Primary / Secondary | Primary Antibody |
| Isotype | Rabbit Ig |
| Clone Name | RB2145/2146 |
| Clonality | Polyclonal |
| Host | Rabbit |
Catalog Number
102-26988-RB
Name
Anti-WISP3 (Center) Antibody
Price(40000 ul)
Pack Size
40000 ul