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SKU: 130-10498-500-RB

Anti-TNI Antibody

RT

Specifications

Specification Details
Application ELISA (recommended work dilution= 1:320,000)Western Blotting (recommended work dilution= 1:1,000-5,000),
Label Unconjugated
Gene ID 7137
Immunogen Immunogen was recombinant protein. This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with the immunogen. The IgG fraction of tissue culture supernatant was purified by Protein G/A affinity chromatography.
Background Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it, myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle. The letter I is given due to its inhibitory character.
Primary / Secondary Primary Antibody
Clone Name 1H5-F4-E11
Clonality Monoclonal
Catalog Number
130-10498-500-RB
Name
Anti-TNI Antibody
Price(500 ug)
Pack Size
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