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SKU: 102-20959-RB

Anti-TNFSF15 (Center) Antibody

Blue Ice

Specifications

Specification Details
Species Reactivity Human
Application WB, IF, FC
Label Unconjugated
Gene ID 9966
Accession No. O95150, NP_005109.2
Immunogen This TNFSF15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-175 amino acids from the Central region of human TNFSF15.
Background The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. An additional isoform encoded by an alternatively spliced transcript variant has been reported but the sequence of this transcript has not been determined. [provided by RefSeq].
Primary / Secondary Primary Antibody
Isotype Rabbit Ig
Clone Name RB21818
Clonality Polyclonal
Host Rabbit
Catalog Number
102-20959-RB
Name
Anti-TNFSF15 (Center) Antibody
Price(400 ul)
Pack Size
400 ul
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