SKU: 130-10951-500-RB
Anti-TK1 (209-230aa) Antibody
RT
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | ELISA (recommended work dilution = 1:320,000) |
| Label | Unconjugated |
| Accession No. | P04183 |
| Immunogen | Immunogen was polypeptide TK1 (29-23aa)-KLH:PGKPGEAVAARKLFAPQQILQC. This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with the immunogen. The IgG fraction of tissue culture supernatant was purified by Protein G/A affinity chromatography. |
| Background | Thymidine Kinase (TK1) is a highly conserved phosphotransferase that is present in most living cells. Thymidine Kinase catalyzes the phosphorylation reaction: deoxythymidine + ATP = deoxythymidine 5'-phosphate + ADP; it is thus involved in the reaction chain to introduce deoxythymidine into the DNA. Thymidine kinase is required for the action of many antiviral drugs, such as azidothymidine (AZT), and is also used to select hybridoma cell lines in the production of monoclonal antibodies. Thymidine Kinase has many clinical applications as it is only present in anticipation of cell division. |
| Primary / Secondary | Primary Antibody |
| Clone Name | 2C2-F10-B10-A2 |
| Clonality | Monoclonal |
| Host | Mouse |
Catalog Number
130-10951-500-RB
Name
Anti-TK1 (209-230aa) Antibody
Price(500 ug)
Pack Size
500 ug