SKU: 130-00010B-50-RB
Anti-TIMP3 Antibody, Biotinylated
In Stock
RT
Specifications
| Specification | Details |
|---|---|
| Application | ELISA (recommended work dilution= 1: 1,000-5,000), Western Blotting (recommended work dilution= 1: 1,000-2,000) |
| Label | Biotin |
| Accession No. | NP_000353 |
| Immunogen | Immunogen was synthetic peptide derived from Human TIMP3. This antibody was produced from a chicken immunized with the immunogen. The IgY fraction was purified from collected egg followed by in-house affinity chromatography. |
| Background | TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases-1, -2, -3 and -4) complex with metalloproteinases such as collagenases, gelatinases and stromelysins, resulting in irreversible inactivation of the metallo-proteinase. TIMP-1 was found to be identical to EPA (erythroidpotentiation activity). Parathyroid hormone has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart and low levels of TIMP-4 are expressed in liver, brain, lung, thymus and spleen. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgY |
| Host | Chicken |
Catalog Number
130-00010B-50-RB
Name
Anti-TIMP3 Antibody, Biotinylated
Price(5000 ug)
Pack Size
5000 ug