SKU: 102-25369-RB
Anti-STAT3 (S727) Antibody
In Stock
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse |
| Application | WB |
| Label | Unconjugated |
| Gene ID | 6774 |
| Accession No. | P40763 |
| Immunogen | This STAT3(S727) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 71-74 amino acids from the human region of human STAT3(S727). |
| Background | Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)- responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity). |
| Primary / Secondary | Primary Antibody |
| Isotype | Rabbit Ig |
| Clone Name | RB60380 |
| Clonality | Polyclonal |
| Host | Rabbit |
Catalog Number
102-25369-RB
Name
Anti-STAT3 (S727) Antibody
Price(20000 ul)
Pack Size
20000 ul