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SKU: 102-26567-RB

Anti-STAT3 Antibody

Blue Ice

Specifications

Specification Details
Species Reactivity Human, Mouse
Application WB
Label Unconjugated
Gene ID 6774
Accession No. P40763
Immunogen This STAT3 antibody is generated from a mouse immunized with a recombinant protein from human.
Background Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)- responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity).
Primary / Secondary Primary Antibody
Isotype IgG2a,κ
Clone Name 1200CT146.104.153
Clonality Monoclonal
Host Mouse
Catalog Number
102-26567-RB
Name
Anti-STAT3 Antibody
Price(100 ul)
Pack Size
100 ul
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