SKU: 102-26228-RB
Anti-SMUG1 Antibody
In Stock
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Application | WB |
| Label | Unconjugated |
| Gene ID | 23583 |
| Accession No. | Q53HV7 |
| Background | Responsible for recognizing base lesions in the genome and initiating base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA and has a preference for single-stranded DNA substrates. The activity is greater against mismatches (U/G) than against matches (U/A). Excised uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5- hydroxymethyluracil (hmU)] in ssDNA and dsDNA but not analogous cytosine derivatives (5-hydroxycytosine and 5-formylcytosine) and other oxidized damage. The activity is damage specificity and salt concentration-dependent. The general order of the preference for ssDNA and dsDNA is the following: ssDNA > dsDNA (G pair) = dsDNA (A pair) at the low salt concentration. At the high concentration dsDNA (G pair) > dsDNA (A pair) > ssDNA. |
| Primary / Secondary | Primary Antibody |
| Clonality | Polyclonal |
| Host | Rabbit |
Catalog Number
102-26228-RB
Name
Anti-SMUG1 Antibody
Price(10000 ul)
Pack Size
10000 ul