SKU: 188-10477-IHC-RB
Anti-Prostate Specific Antigen Antibody
In Stock
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Cat |
| Application | IHC (Prediluted format) |
| Label | Unconjugated |
| Gene ID | 354 |
| Accession No. | P07288 |
| Immunogen | PSA (p3) from human sperm plasma was used as the immunogen for the Prostate Specific Antigen antibody. |
| Background | Recognizes a single protein of 33-34kDa, identified as the prostate specific antigen (PSA). This mAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This mAb makes an excellent pair with mAb A67-B/E3 for PSA tests. |
| Primary / Secondary | Primary Antibody |
| Isotype | Mouse IgG1, kappa |
| Concentration | Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide, *For IHC use only* |
| Host | Mouse |
Catalog Number
188-10477-IHC-RB
Name
Anti-Prostate Specific Antigen Antibody
Price(700 ml)
Pack Size
700 ml