SKU: 102-21188-RB
Anti-PCDHA7 (Center) Antibody
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | WB, IHC-P |
| Label | Unconjugated |
| Gene ID | 56141 |
| Accession No. | Q9UN72, Q9Y5H5, NP_114040.1, NP_061733.1 |
| Immunogen | This PCDHA7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 272-3 amino acids from the Central region of human PCDHA7. |
| Background | This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. |
| Primary / Secondary | Primary Antibody |
| Isotype | Rabbit Ig |
| Clone Name | RB30194 |
| Clonality | Polyclonal |
| Host | Rabbit |
Catalog Number
102-21188-RB
Name
Anti-PCDHA7 (Center) Antibody
Price(400 ul)
Pack Size
400 ul