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SKU: 102-21543-RB

Anti-MUC1/EMA (C-term) Antibody

In Stock Blue Ice

Specifications

Specification Details
Species Reactivity Human
Application WB, IHC-P
Label Unconjugated
Gene ID 4582
Accession No. P15941, NP_001018016.1, NP_001037856.1, NP_001018017.1, NP_001037855.1
Immunogen This MUC1/EMA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1176-125 amino acids from the C-terminal region of human MUC1/EMA.
Background This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 2 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 2 to 12 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined. [provided by RefSeq].
Primary / Secondary Primary Antibody
Isotype Rabbit Ig
Clone Name RB33144
Clonality Polyclonal
Host Rabbit
Catalog Number
102-21543-RB
Name
Anti-MUC1/EMA (C-term) Antibody
Price(40000 ul)
Pack Size
40000 ul
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