SKU: 102-23989-RB
Anti-Mouse PDCD6 (Center) Antibody
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Mouse |
| Application | Western Blot |
| Label | Unconjugated |
| Gene ID | 10016 |
| Accession No. | O75340, P12815 |
| Immunogen | This PDCD6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 13-137 amino acids from the Central region of human PDCD6. |
| Background | Calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death. May mediate Ca(2+)- regulated signals along the death pathway (By similarity). Calcium-dependent adapter necessary for the association between PDCD6IP and TSG11. Interaction with DAPK1 can accelerate apoptotic cell death by increasing caspase-3 activity. May inhibit KDR/VEGFR2-dependent angiogenesis; the function involves inhibition of VEGF-induced phosphoprylation of the Akt signaling pathway. Seems to play a role in the regulation of the distribution and function of MCOLN1 in the endosomal pathway. Isoform 2 has a lower Ca(2+) affinity than isoform 1. Isoform 1 and, to a lesser extend, isoform 2, can stabilize SHISA5. |
| Primary / Secondary | Primary Antibody |
| Isotype | Rabbit Ig |
| Clone Name | RB49787 |
| Clonality | Polyclonal |
| Host | Rabbit |
Catalog Number
102-23989-RB
Name
Anti-Mouse PDCD6 (Center) Antibody
Price(400 ul)
Pack Size
400 ul