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SKU: 102-21087-RB

Anti-Mouse PCDHGC5 (Center) Antibody

In Stock Blue Ice

Specifications

Specification Details
Species Reactivity Mouse
Application WB, IHC-P
Label Unconjugated
Gene ID 56097
Accession No. Q9Y5F6, NP_115783.1
Immunogen This PCDHGC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 499-526 amino acids from the Central region of human PCDHGC5.
Background This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
Primary / Secondary Primary Antibody
Isotype Rabbit Ig
Clone Name RB31976
Clonality Polyclonal
Host Rabbit
Catalog Number
102-21087-RB
Name
Anti-Mouse PCDHGC5 (Center) Antibody
Price(40000 ul)
Pack Size
40000 ul
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