SKU: 188-10084-2-RB
Anti-Melan-A Antibody
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Application | FACS, WB, IF, IP, IHC (Prediluted format) |
| Label | Unconjugated |
| Gene ID | 2315 |
| Accession No. | Q16655 |
| Immunogen | Recombinant human Melan-A protein was used as the immunogen for this antibody. |
| Background | This antibody recognizes a protein doublet of 2-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. There are seven other melanoma associated antigens recognized by autologous cytotoxic T cells: MAGE-1, MAGE-3, tyrosinase, gp1, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MART-1 antibody labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. The antibody does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. |
| Primary / Secondary | Primary Antibody |
| Isotype | Mouse IgG2b, kappa |
| Concentration | 0.2 mg/ml in 1X PBS (pH 7.4) with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide |
| Host | Mouse |
Catalog Number
188-10084-2-RB
Name
Anti-Melan-A Antibody
Price(100 ug)
Pack Size