SKU: 144-65959-100-RB
Anti-HEXA Antibody
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse |
| Application | WB |
| Label | Unconjugated |
| Gene ID | 3073 |
| Accession No. | P06865 |
| Background | This gene encodes a member of the glycosyl hydrolase 2 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons, the underlying cause of neurodegenerative disorders termed the GM2 gangliosidoses, including Tay-Sachs disease (GM2-gangliosidosis type I). Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Clonality | Polyclonal |
| Host | Rabbit |
Catalog Number
144-65959-100-RB
Name
Anti-HEXA Antibody
Price(100 ul)
Pack Size